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Carbon-Based Quantum Dots for Electrochemical Detection of Monoamine Neurotransmitters—Review

Saheed E. ElugokeDepartment of Chemistry, School of Physical and Chemical Sciences, Faculty of Natural and Agricultural Sciences, North-West University (Mafikeng Campus), Mmabatho 2735, South AfricaAbolanle S. AdekunleDepartment of Chemistry, Obafemi Awolowo University, Ile-Ife 220005, NigeriaOmolola E. FayemiDepartment of Chemistry, School of Physical and Chemical Sciences, Faculty of Natural and Agricultural Sciences, North-West University (Mafikeng Campus), Mmabatho 2735, South AfricaBhekie B. MambaNanotechnology and Water Sustainability Research Unit, College of Science, Engineering and Technology, University of South Africa, Johannesburg 1709, South AfricaEl‐Sayed M. SherifCenter of Excellence for Research in Engineering Materials (CEREM), King Saud University, P.O. Box 800, Al-Riyadh 11421, Saudi ArabiaEno E. EbensoDepartment of Chemistry, College of Science, Engineering and Technology, University of South Africa, Roodepoort 1710, South Africa

2020en

ABI

Annotatsiya

Imbalance in the levels of monoamine neurotransmitters have manifested in severe health issues. Electrochemical sensors have been designed for their determination, with good sensitivity recorded. Carbon-based quantum dots have proven to be an important component of electrochemical sensors due to their high conductivity, low cytotoxicity and opto-electronic properties. The quest for more sensitive electrodes with cheaper materials led to the development of electrochemical sensors based on carbon-based quantum dots for the detection of neurotransmitters. The importance of monoamine neurotransmitters (NTs) and the good electrocatalytic activity of carbon and graphene quantum dots (CQDs and GQDs) make the review of the efforts made in the design of such sensors for monoamine NTs of huge necessity. The differences and the similarities between these two quantum dots are highlighted prior to a discussion of their application in electrochemical sensors over the last ten years. Compared to other monoamine NTs, dopamine (DA) was the most studied with GQDs and CQD-based electrochemical sensors.

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DOI: 10.3390/bios10110162

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