Volatile Oils from the Aerial Parts of <i>Eremophila maculata</i> and Their Antimicrobial Activity
Fadia S. YoussefDepartment of Pharmacognosy, Faculty of Pharmacy, Ain Shams University, Abbassia, 11566-Cairo, EgyptRazan HamoudInstitute of Pharmacy and Molecular Biotechnology, Heidelberg University, Im Neuenheimer, Feld 364, D-69120, Heidelberg, (phone: +49-6221-544880; fax: +49-6221-544884)Mohamed L. AshourDepartment of Pharmacognosy, Faculty of Pharmacy, Ain Shams University, Abbassia, 11566-Cairo, EgyptAbdel Nasser B. SingabDepartment of Pharmacognosy, Faculty of Pharmacy, Ain Shams University, Abbassia, 11566-Cairo, EgyptMichaël WinkInstitute of Pharmacy and Molecular Biotechnology, Heidelberg University, Im Neuenheimer, Feld 364, D-69120, Heidelberg, (phone: +49-6221-544880; fax: +49-6221-544884)
2014en
ABI
Annotatsiya
The essential oils isolated from the fresh flowers, fresh leaves, and both fresh and air-dried stems of Eremophila maculata (Scrophulariaceae) were characterized by GC-FID and GC/MS analyses. Sabinene was the major component in most of the oils, followed by limonene, α-pinene, benzaldehyde, (Z)-β-ocimene, and spathulenol. The leaf and flower essential oils showed antibacterial and antifungal activity against five Gram-positive and four Gram-negative bacterial strains, multi-resistant clinical isolates from patients, i.e., methicillin-resistant Staphylococcus aureus (MRSA), as well as two yeasts. Minimum inhibitory concentrations (MICs) and minimum microbicidal concentrations (MMCs) were between 0.25 and 4 mg/ml.
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