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Affinity of polyphenols for lipid bilayers

Tsutomu NakayamaSchool of Food and Nutritional Sciences, University of Shizuoka, JapanToshihiko HashimotoSchool of Food and Nutritional Sciences, University of Shizuoka, 52-1 Yada, Shizuoka 422-8526, JapanKatsuko KajiyaSchool of Food and Nutritional Sciences, University of Shizuoka, 52-1 Yada, Shizuoka 422-8526, JapanShigenori KumazawaSchool of Food and Nutritional Sciences, University of Shizuoka, 52-1 Yada, Shizuoka 422-8526, Japan
2000en
ABI

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Interaction of tea catechins with lipid bilayers has been investigated with liposome systems. Epicatechin gallate had the highest affinity for lipid bilayers, followed by epigallocatechin gallate, epicatechin, and epigallocatechin. Epicatechin gallate and epigallocatechin gallate in the surface of lipid bilayer perturbed the membrane structure.

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