Understanding Wax Printing: A Simple Micropatterning Process for Paper-Based Microfluidics
Emanuel CarrilhoDepartment of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, Massachusetts 02138, and Instituto de Química de São Carlos, Universidade de São Paulo, 13566-590 São Carlos-SP, BrazilAndres W. MartinezDepartment of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, Massachusetts 02138, and Instituto de Química de São Carlos, Universidade de São Paulo, 13566-590 São Carlos-SP, BrazilGeorge M. WhitesidesDepartment of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, Massachusetts 02138, and Instituto de Química de São Carlos, Universidade de São Paulo, 13566-590 São Carlos-SP, Brazil
2009en
ABI
Annotatsiya
This technical note describes a detailed study on wax printing, a simple and inexpensive method for fabricating microfluidic devices in paper using a commercially available printer and hot plate. The printer prints patterns of solid wax on the surface of the paper, and the hot plate melts the wax so that it penetrates the full thickness of the paper. This process creates complete hydrophobic barriers in paper that define hydrophilic channels, fluid reservoirs, and reaction zones. The design of each device was based on a simple equation that accounts for the spreading of molten wax in paper.
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