Methyl Carnosate, an Antibacterial Diterpene Isolated from <i>Salvia officinalis</i> Leaves
Elisa ClimatiDepartment for the Innovation in Biological, Agro-food and Forest systems, Laboratory of Plant Cytology and Biotechnology, Tuscia University, Largo dell'Università blocco D, 01100 Viterbo, ItalyFabio MastrogiovanniDepartment for the Innovation in Biological, Agro-food and Forest systems, Laboratory of Plant Cytology and Biotechnology, Tuscia University, Largo dell'Università blocco D, 01100 Viterbo, ItalyMaría Cristina ValeriDepartment for the Innovation in Biological, Agro-food and Forest systems, Laboratory of Plant Cytology and Biotechnology, Tuscia University, Largo dell'Università blocco D, 01100 Viterbo, ItalyLaura SalviniToscana Life Sciences, Via Fiorentina 1, 53100 Siena, ItalyClaudia BonechiDepartment of Pharmaceutical and Applied Chemistry, University of Siena, Via A. Moro 2, 53100 Siena, ItalyNilufar Zokirzhonovna MamadalievaInstitute of the Chemistry of Plant Substances, Mirzo Ulugbek Str 77, Tashkent 100170, UzbekistanDilfuza EgamberdievaDepartment of Biotechnology and Microbiology, National University of Uzbekistan, Tashkent 100174, UzbekistanAnna Rita TaddeiDepartment for the Innovation in Biological, Agro-food and Forest systems, Laboratory of Plant Cytology and Biotechnology, Tuscia University, Largo dell'Università blocco D, 01100 Viterbo, ItalyAntonio TiezziDepartment for the Innovation in Biological, Agro-food and Forest systems, Laboratory of Plant Cytology and Biotechnology, Tuscia University, Largo dell'Università blocco D, 01100 Viterbo, Italy
ABI
Annotatsiya
Ethanolic extracts of Salvia officinalis leaves demonstrated antibacterial activity against Bacillus cereus. Fractionation of the extracts led to the isolation of the most active antibacterial compound, which, from spectroscopic and LC-MS evidence, was proved to be the diterpene, methyl carnosate.
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