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Studies on the Constituents of Lagochilus leiacanthus (Labiatae)

Megumi FurukawaSchool of Pharmacy, Nihon UniversityHideya SuzukiDepartment of Chemistry, College of Humanities and Sciences, Nihon UniversityMitsuko MakinoDepartment of General Education, College of Humanities and Sciences, Nihon UniversityShoujiro OgawaDepartment of Chemistry, College of Humanities and Sciences, Nihon UniversityTakashi IidaDepartment of Chemistry, College of Humanities and Sciences, Nihon UniversityYasuo FujimotoDepartment of General Education, College of Humanities and Sciences, Nihon University
2011en
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Two flavanones, 5,2',6'-trihydroxy-7,8-dimethoxyflavanone (1), 5,2',6'-trihydroxy-6,7,8-trimethoxyflavanone (2) and their 2'-O-β-D-glucosides (3, 4), and a neoclerodane-type diterpene, 15-demethoxyscupolin I (5), together with twenty-eight known compounds were isolated from the extracts of Lagochilus leiacanthus. The structures of the new compounds were determined by spectroscopic means. The two new flavanones and some known flavonoids showed the inhibitory activity on the release of β-hexosaminidase from RBL-2H3 cells.

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