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Recent progress on magnetic iron oxide nanoparticles: synthesis, surface functional strategies and biomedical applications

Wei WuKey Laboratory of Artificial Micro- and Nano-structures of Ministry of Education, School of Physics and Technology, Wuhan University , Wuhan 430072, People’s Republic of ChinaZhaohui WuDepartment of Chemical Engineering, Kyung Hee University , KoreaTaekyung YuDepartment of Chemical Engineering, Kyung Hee University , KoreaChangzhong JiangKey Laboratory of Artificial Micro- and Nano-structures of Ministry of Education, School of Physics and Technology, Wuhan University , Wuhan 430072, People’s Republic of ChinaWoo Sik KimDepartment of Chemical Engineering, Kyung Hee University , Korea
2015en
ABI

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applications, the IONPs must have combined properties of high magnetic saturation, stability, biocompatibility, and interactive functions at the surface. Moreover, the surface of IONPs could be modified by organic materials or inorganic materials, such as polymers, biomolecules, silica, metals, etc. The new functionalized strategies, problems and major challenges, along with the current directions for the synthesis, surface functionalization and bioapplication of IONPs, are considered. Finally, some future trends and the prospects in these research areas are also discussed.

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