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Two New Polyporusterones Isolated from the Sclerotia of Polyporus umbellatus

Weiwei ZhouInstitute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical CollegeWenhan LinState Key Laboratory of Natural and Biomimetic Drugs, Peking UniversityShun‐Xing GuoInstitute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College
2007en
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In the course of searching for marker components, two new polyporusterones were isolated from the sclerotia of Polyporus umbellatus, together with another three known analogs. The structures of the new ones were elucidated as (20S,22R,24R)-16,22-epoxy-3beta,14alpha,23beta,25-tetrahydroxyergost-7-en-6-one (1) and (23R,24R,25R)-23,26-epoxy-3beta,14alpha,21alpha,22alpha-tetrahydroxyergost-7-en-6-one (2) by chemical and spectroscopic means, including HR-FAB-MS, 1D- and 2D-NMR.

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