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Beneficial Oxidative Stress-Related trans-Resveratrol Effects in the Treatment and Prevention of Breast Cancer

Alessandra QuartaCNR Nanotec, Institute of Nanotechnology, Via Monteroni, 73100 Lecce, ItalyAntonio GaballoCNR Nanotec, Institute of Nanotechnology, Via Monteroni, 73100 Lecce, ItalyBiswajita PradhanPost Graduate Department of Botany, Berhampur University, Bhanja Bihar, Berhampur 760007, Odisha, IndiaSrimanta PatraCancer and Cell Death Laboratory, Department of Life Science, National Institute of Technology Rourkela, Rourkela 769001, Odisha, IndiaMrutyunjay JenaPost Graduate Department of Botany, Berhampur University, Bhanja Bihar, Berhampur 760007, Odisha, IndiaAndrea RagusaCNR Nanotec, Institute of Nanotechnology, Via Monteroni, 73100 Lecce, Italy

2021en

ABI

Annotatsiya

Resveratrol is one of the most investigated polyphenols for its multiple biological activities and many beneficial effects. These are mainly related to its ability to scavenge free radicals and reduce oxidative stress. Resveratrol has also been shown to have the ability to stimulate the production of antioxidant enzymes, which interact with numerous signaling pathways involved in tumor development, and to possess side effects associated with the use of chemotherapy drugs. In this review article we summarized the main discoveries about the impact resveratrol can have in helping to prevent, as well as adjuvant treating, breast cancer. A brief overview of the primary sources of resveratrol as well as some approaches for improving its bioavailability have been also discussed.

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Identifikatorlar

DOI: 10.3390/app112211041

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