Indices of multilocus linkage disequilibrium
Paul‐Michael AgapowDepartment of Biology, Imperial College, Silwood Park, Ascot, Berkshire, SL5 7PY, UKAustin BurtDepartment of Biology, Imperial College, Silwood Park, Ascot, Berkshire, SL5 7PY, UK
2001en
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Abstract Linkage disequilibrium is an ubiquitous biological phenomenon. However a common metric for disequilibrium – the index of association or I A – is dependent on sample size. In this paper we present a modification of I A that removes this dependency. This method has been implemented in a software package.
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