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AASLD guidelines for the treatment of hepatocellular carcinoma

Julie K. HeimbachDivision of Transplant Surgery, William J. von Liebig Transplant Center, Mayo Clinic,Rochester,MNLaura KulikDepartment of Medicine, Division of Gastroenterology and Hepatology, Northwestern University,Chicago,ILRichard S. FinnDepartment of Medicine, Division of Hematology and Oncology, David Geffen School of Medicine at the University of California, Los Angeles, Santa Monica Geffen School of Medicine at UCLA,Los Angeles,CaliforniaClaude B. SirlinLiver Imaging Group, Department of Radiology,University of California,San DiegoMichaël AbécassisNorthwestern University Feinberg School of Medicine, Chicago,ILLewis R. RobertsDivision of Gastroenterology and Hepatology, Mayo Clinic,Rochester,MNAndrew X. ZhuMassachusetts General Hospital Cancer Center, Harvard Medical School,Boston,MAM. Hassan MuradMayo Clinic Evidence-based Practice Center, Mayo Clinic,Rochester,MNJorge A. MarreroDigestive and Liver Diseases Division, Department of Internal Medicine, UT Southwestern Medical Center,Dallas,TX

2017en

ABI

Annotatsiya

This document presents official recommendations of the American Association for the Study of Liver Diseases (AASLD) on the surveillance, diagnosis, and treatment of hepatocellular carcinoma (HCC) occurring in the setting of adults with cirrhosis. Unlike previous AASLD practice guidelines, the current guideline was developed in compliance with the Institute of Medicine standards for trustworthy practice guidelines and uses the Grading of Recommendation Assessment, Development and Evaluation (GRADE) approach. Multiple systematic reviews of the literature were conducted to support the recommendations in this practice guideline. An enhanced understanding of the guideline can be obtained by reading the applicable portions of the systematic reviews. In addition, more detailed information may be found in the associated guidance document related to clinically important aspects of HCC that lacked sufficient evidence to warrant a systematic review.

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DOI: 10.1002/hep.29086

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