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Effect of the physicochemical changes in the antimicrobial durability of green synthesized silver nanoparticles during their long-term storage

Giyaullah HabibullahDepartment of Biochemistry and Microbiology, University of Chemistry and Technology, Technická 3, 166 28, Prague, Czech RepublicJitka ViktorováDepartment of Biochemistry and Microbiology, University of Chemistry and Technology, Technická 3, 166 28, Prague, Czech RepublicPavel UlbrichDepartment of Biochemistry and Microbiology, University of Chemistry and Technology, Technická 3, 166 28, Prague, Czech RepublicTomáš RumlDepartment of Biochemistry and Microbiology, University of Chemistry and Technology, Technická 3, 166 28, Prague, Czech Republic
2022en
ABI

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by the freshly synthesized and 15 day old AgNPs; however, the inhibition rate escalated after a month and the highest rate of inhibition was observed with the particles between 2 months to 6 months of storage. After 6 months, we observed the particles losing their antimicrobial potential gradually, that lasted throughout the rest of our study period. This observation was in accord with the physicochemical changes that AgNPs were undergoing with time. By deepening our understanding of the changes in the physicochemical properties of green synthesized AgNPs over time, this study contributes to the development of more effective, durable, and potent AgNPs.

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