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Potassium hexacyanoferrate(<scp>ii</scp>)—a new cyanating agent for the palladium-catalyzed cyanation of aryl halides

Thomas SchareinaLeibniz-Institut fur Organische Katalyse an der Universitat Rostock e.V., Buchbinderstr. 5-6, 18055 Rostock, Germany. matthiasAlexander ZapfLeibniz-Institut für Organische Katalyse an der Universität Rostock e.V., Buchbinderstr. 5–6, 18055 Rostock, GermanyMatthias BellerLeibniz-Institut für Organische Katalyse an der Universität Rostock e.V., Buchbinderstr. 5–6, 18055 Rostock, Germany
2004en
ABI

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A new advantageous cyanating agent, potassium hexacyanoferrate(II), is described for the palladium-catalyzed cyanation of aryl halides. All cyanide ions on the iron(II) center can be transferred to the aryl halide using palladium(II) acetate and dppf as the catalyst. Under optimized reaction conditions good yields of benzonitriles and unprecedented catalyst productivities are observed.

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