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Natural products in drug discovery: advances and opportunities

Atanas G. AtanasovDepartment of Pharmacognosy, University of Vienna, Vienna, Austria. [email protected]Sergey B. ZotchevDepartment of Pharmacognosy, University of Vienna, Vienna, AustriaVerena M. DirschDepartment of Pharmacognosy, University of Vienna, Vienna, Austriathe International Natural Product Sciences TaskforceDepartment of Pharmacognosy, Faculty of Pharmacy, Gazi University, Ankara, Turkeyİlkay Erdoğan OrhanPolish Mother's Memorial Hospital Research Institute (PMMHRI), Łodz, PolandMaciej BanachDepartment of Pharmacognosy, University of Vienna, Vienna, AustriaJudith M. RollingerDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, Università degli Studi di Messina, Messina, ItalyDavide BarrecaMolecular Systems Biology (MOSYS), Department of Evolutionary and Functional Ecology, University of Vienna, Vienna, AustriaWolfram WeckwerthInstitute of Pharmaceutical Sciences, Department of Pharmacognosy, University of Graz, Graz, AustriaRudolf BauerDepartment of Biomolecular Sciences, The Weizmann Institute of Science, Rehovot, IsraelEdward A. BayerSami Labs Limited, 19/1, 19/2, First Main, Second Phase, Peenya Industrial Area, Bangalore, Karnataka, IndiaMuhammed MajeedLake Erie College of Osteopathic Medicine, Bradenton, FL, USAAnupam BishayeeInstitute of Pharmaceutical Sciences, Department of Pharmaceutical Chemistry, University of Graz, Graz, AustriaValery N. BochkovInstitute of Analytical Chemistry and Radiochemistry, Leopold-Franzens University of Innsbruck and Austrian Drug Screening Institute — ADSI, CCB — Center of Chemistry and Biomedicine, Innsbruck, AustriaGünther K. BonnCentre for Healthy Brain Ageing (CHeBA), School of Psychiatry, University of New South Wales, Sydney, New South Wales, AustraliaNady BraidyInstitute of Pharmaceutical Sciences, Department of Pharmacognosy, University of Graz, Graz, AustriaFranz BučarLaboratory of Foodomics, Bioactivity and Food Analysis Department, Institute of Food Science Research CIAL (UAM-CSIC), Madrid, SpainAlejandro CifuentesClinical Psychology Service, Health Department, Fondazione IRCCS 'Casa Sollievo della Sofferenza', San Giovanni Rotondo, ItalyGrazia D’OnofrioEvotec (UK) Ltd, Oxford, UKMichael J. BodkinDepartment of Pharmacy, College of Pharmacy, Seoul National University, Seoul, South KoreaMarc DiederichJacqui Wood Cancer Centre, Division of Cellular Medicine, School of Medicine, University of Dundee, Dundee, UKAlbena T. Dinkova‐KostovaDepartment of Pharmaceutical Biology, Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University, Mainz, GermanyThomas EfferthKhalid El BairiNicolas ArkellsDepartment of Pharmacology, University of Cambridge, Cambridge, UKTai-Ping FanNeuroimmunology and Neurochemistry Research Group, Department of Psychiatry and Psychotherapy, Medical Center – University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, GermanyBernd L. FiebichInstitute of Pharmacology and the Gaston H. Glock Research Laboratories for Exploratory Drug Development, Center of Physiology and Pharmacology, Medical University of Vienna, Vienna, AustriaMichael FreissmuthLaboratory of Metabolomics, The Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, Plovdiv, BulgariaMilen I. GeorgievResearch Department of Pharmaceutical and Biological Chemistry, UCL School of Pharmacy, London, UKSimon GibbonsMRC Lifecourse Epidemiology Unit and NIHR Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UKKeith M. GodfreyInstitute of Pharmacology and the Gaston H. Glock Research Laboratories for Exploratory Drug Development, Center of Physiology and Pharmacology, Medical University of Vienna, Vienna, AustriaChristian W. GruberUCB Pharma Ltd, Slough, UKJag HeerInstitute for Cell Biology, Biocenter, Medical University of Innsbruck, Innsbruck, AustriaLukas A. HuberLaboratory of Foodomics, Bioactivity and Food Analysis Department, Institute of Food Science Research CIAL (UAM-CSIC), Madrid, SpainElena IbáñezICBAS-Instituto de Ciências Biomédicas Abel Salazar & CIIMAR, Universidade do Porto, Porto, PortugalAnake KijjoaDepartment of Pharmacognosy and Molecular Basis of Phytotherapy, Medical University of Warsaw, Warsaw, PolandAnna K. KissSchool of Chinese Medicine, Hong Kong Baptist University, Hong Kong, ChinaAiping LüAllelopathy Group, Department of Organic Chemistry, Institute of Biomolecules (INBIO), Campus de Excelencia Internacional (ceiA3), School of Science, University of Cadiz, Cadiz, SpainFrancisco A. Macı́asMark J.S. MillerDepartment of Pharmaceutical Botany, 'Iuliu Haţieganu' University of Medicine and Pharmacy, Cluj-Napoca, RomaniaAndrei MocanDepartment of Microbial Natural Products, Helmholtz-Institute for Pharmaceutical Research Saarland, Helmholtz Centre for Infection Research and Department of Pharmacy, Saarland University, Saarbrücken, GermanyRolf MüllerDepartment of Biomedical and Biotechnological Sciences, University of Catania, Catania, ItalyFerdinando NicolettiDepartment of Biology, The University of Texas at San Antonio, San Antonio, TX, USAGeorge PerryDepartment of Drug Science, University of Catania, Catania, ItalyValeria PittalàDipartimento di Farmacia, University of Salerno, Fisciano, ItalyLuca RastrelliÉcole Polytechnique Fédérale de LausanneMichael RistowInstitute of Food Sciences, National Research Council, Avellino, ItalyGian Luigi RussoNational Institute for Agricultural and Veterinary Research (INIAV), Vila do Conde, PortugalA. Sanches‐SilvaDepartment of Pharmaceutical and Medicinal Chemistry, Institute of Pharmacy, Paracelsus Medical University Salzburg, Salzburg, AustriaDaniela SchusterThe NatPro Centre, School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, Dublin, IrelandHelen SheridanIndependent Laboratory of Natural Products Chemistry, Medical University of Lublin, Lublin, PolandKrystyna Skalicka‐WoźniakDepartment of Pharmacognosy and Natural Products Chemistry, Faculty of Pharmacy, National and Kapodistrian University of Athens, Panepistimioupolis Zografou, Athens, GreeceLéandros SkaltsounisLaboratory of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Santiago de Compostela, Santiago de Compostela, SpainEduardo Sobarzo‐SánchezJanssen Pharmaceuticals Research & Development, San Diego, CA, USADavid S. BredtInstitute of Pharmacy/Pharmacognosy, Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innsbruck, AustriaHermann StuppnerResearch Group on Community Nutrition and Oxidative Stress, and Health Research Institute of the Balearic Islands (IdISBa), Department of Fundamental Biology and Health Sciences, University of Balearic Islands, Palma de Mallorca, SpainAntoni SuredaInstitute of Molecular Biology 'Roumen Tsanev', Department of Biochemical Pharmacology and Drug Design, Bulgarian Academy of Sciences, Sofia, BulgariaNikolay TzvetkovInstitute of Biomembranes, Bioenergetics and Molecular Biotechnologies, Italian National Council of Research, Bari, ItalyRosa Anna VaccaInflammation Research Center, San Diego, CA, USABharat B. AggarwalDepartment of Clinical Sciences, Università Politecnica delle Marche, Ancona, ItalyMaurizio BattinoDepartment of Clinical Sciences, Università Politecnica delle Marche, Ancona, ItalyFrancesca GiampieriInstitute of Pharmacy and Molecular Biotechnology, Heidelberg University, Heidelberg, GermanyMichaël WinkSchool of Pharmaceutical Sciences, University of Geneva, CMU, Geneva, SwitzerlandJean‐Luc WolfenderInternational Research Center for Food Nutrition and Safety, Jiangsu University, Zhenjiang, ChinaJianbo XiaoOral and Maxillofacial Radiology, Applied Oral Sciences and Community Dental Care, Faculty of Dentistry, The University of Hong Kong, Hong Kong, ChinaAndy Wai Kan YeungTeam Bio-PeroxIL, 'Biochemistry of the Peroxisome, Inflammation and LipidMetabolism' (EA7270)/University Bourgogne Franche-Comté/Inserm, Dijon, FranceGérard LizardBionorica SE, Neumarkt/Oberpfalz, GermanyMichael PoppResearch Group 'Pharmacognosy and Phytotherapy', UCL School of Pharmacy, London, UKMichael HeinrichResearch Center for Functional Genomics, Biomedicine and Translational Medicine, Institute of Doctoral Studies, 'Iuliu Hatieganu' University of Medicine and Pharmacy, Cluj-Napoca, RomaniaIoana Berindan-NeagoeGerman Centre for Infection Research (DZIF), Partner Site Hannover, Braunschweig, GermanyMarc StadlerInternational Research Center for Food Nutrition and Safety, Jiangsu University, Zhenjiang, ChinaMaria DagliaNatural Products Laboratory, Institute of Biology, Leiden University, Leiden, NetherlandsRobert VerpoorteUniversità degli Studi di Firenze, NEUROFARBA Dept, Sezione di Scienze Farmaceutiche, Florence, ItalyClaudiu T. SupuranUniversità degli Studi di Firenze, NEUROFARBA Dept, Sezione di Scienze Farmaceutiche, Florence, Italy. [email protected]
2021en
ABI

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