Electrochemical <i>E</i>-Selective Semireductive Dicarboxylation of Aryl Alkynes with CO<sub>2</sub>
Lan ZhaoState Key Laboratory and Institute of Elemento-Organic Chemistry, Frontiers Science Center for New Organic Matter, College of Chemistry, Nankai University, Tianjin 30007, P. R. ChinaWen‐Jun XieState Key Laboratory and Institute of Elemento-Organic Chemistry, Frontiers Science Center for New Organic Matter, College of Chemistry, Nankai University, Tianjin 30007, P. R. ChinaZheng-Zheng MengState Key Laboratory and Institute of Elemento-Organic Chemistry, Frontiers Science Center for New Organic Matter, College of Chemistry, Nankai University, Tianjin 30007, P. R. ChinaHongru LiCollege of Pharmacy, Nankai University, Tianjin 300350, P. R. ChinaLiang‐Nian HeState Key Laboratory and Institute of Elemento-Organic Chemistry, Frontiers Science Center for New Organic Matter, College of Chemistry, Nankai University, Tianjin 30007, P. R. China
2024en
ABI
Annotatsiya
Herein, we report an electrochemical protocol for the dicarboxylation of aryl alkynes using CO2. With a graphite rod as the cathode and Al as the sacrificial anode, a series of valuable butenedioic acids are obtained in moderate to excellent yields with an E/Z ratio up to 50:1. This method features high E-selectivity, high step and atom economy, easy scalability, and a nice substrate scope, which renders it appealing for promising applications in organic synthesis and materials chemistry.
Hali tarjima qilinmagan
Identifikatorlar
Iqtiboslar va manbalar
4 ta iqtibos0 ta foydalanilgan manba