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Pre-conditioning modifies the TME to enhance solid tumor CAR T cell efficacy and endogenous protective immunity

John P. MuradDepartment of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA 91010, USADileshni TilakawardaneDepartment of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA 91010, USAAnthony K. ParkDepartment of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA 91010, USA; Irell and Manella Graduate School of Biological Sciences, City of Hope, Duarte, CA 91010, USALupita S. LopezDepartment of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA 91010, USA; Irell and Manella Graduate School of Biological Sciences, City of Hope, Duarte, CA 91010, USACari A. YoungDepartment of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA 91010, USA; Irell and Manella Graduate School of Biological Sciences, City of Hope, Duarte, CA 91010, USAJackson GibsonDepartment of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA 91010, USAYukiko YamaguchiDepartment of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA 91010, USAHee Jun LeeDepartment of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA 91010, USAKelly T. KennewickDepartment of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA 91010, USABrenna GittinsDepartment of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA 91010, USAWen-Chung ChangDepartment of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA 91010, USAChau P. TranDepartment of Urology, University of California, Los Angeles, Los Angeles, CA 90095, USACatalina MartínezDepartment of Clinical and Translational Project Development, City of Hope, Duarte, CA 91010, USAAnna M. WuDepartment of Molecular Imaging and Therapy, City of Hope, Duarte, CA 91010, USARobert E. ReiterDepartment of Urology, University of California, Los Angeles, Los Angeles, CA 90095, USATanya B. DorffDepartment of Medical Oncology and Therapeutics Research, City of Hope, Duarte, CA 91010, USAStephen J. FormanDepartment of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA 91010, USA; Department of Immuno-Oncology, Beckman Research Institute of City of Hope, Duarte, CA 91010, USASaul J. PricemanDepartment of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA 91010, USA; Department of Immuno-Oncology, Beckman Research Institute of City of Hope, Duarte, CA 91010, USA. Electronic address: [email protected]
2021en
ABI

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