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COVID-19 and diabetes: Association intensify risk factors for morbidity and mortality

Prateek SharmaChitkara College of Pharmacy, Chitkara University, Punjab, India; Government Pharmacy College, Nagrota Bagwan, Kangra, Himachal Pradesh, IndiaTapan BehlChitkara College of Pharmacy, Chitkara University, Punjab, India. Electronic address: [email protected]Neelam SharmaChitkara College of Pharmacy, Chitkara University, Punjab, IndiaSukhbir SinghChitkara College of Pharmacy, Chitkara University, Punjab, IndiaAjmer Singh GrewalGuru Gobind Singh College of Pharmacy, Yamuna Nagar, Haryana, IndiaAli AlbarratiRehabilitation Health Sciences, College of Applied Medical Sciences, King Saud University, Saudi ArabiaMohammed AlbrattyDepartment of Pharmaceutical Chemistry, College of Pharmacy, Jazan University, Jazan, Saudi ArabiaAbdulkarim M. MerayaPharmacy Practice Research Unit, Department of Clinical Pharmacy, College of Pharmacy, Jazan University, Jazan, Saudi ArabiaSimona BungăuDepartment of Pharmacy, Faculty of Medicine and Pharmacy, University of Oradea, Oradea, Romania; Doctoral School of Biomedical Sciences, University of Oradea, Oradea, Romania. Electronic address: [email protected]
2022en
ABI

Annotatsiya

Diabetes is a condition that affects a large percentage of the population and it is the leading cause of a wide range of costly complications. Diabetes is linked to a multi-fold increase in mortality and when compared to non-diabetics, the intensity and prevalence of COVID-19 ailment among diabetic individuals are more. Since its discovery in Wuhan, COVID-19 has grown rapidly and shown a wide range of severity. Temperature, lymphopenia, non-productive cough, dyspnoea, and tiredness are recognized as the characteristic of individuals infected with COVID-19 disease. In COVID-19 patients, diabetes and other related comorbidities are substantial predictors of disease and mortality. According to a recent study, SARS-CoV-2 (the virus responsible for covid-19 disease) may also lead to direct pancreatic harm, which could aggravate hyperglycemia and potentially cause the establishment of diabetes in formerly non-diabetic individuals. This bidirectional association of COVID-19 and diabetes load the burden on health care professionals throughout the world. It is recommended that gliptin medications be taken moderately, blood glucose levels must be kept under control, ACE inhibitors should be used in moderation, decrease the number of avoidable hospitalizations, nutritional considerations, and some other prevention measures, such as immunization, are highly recommended. SARS-CoV-2 may cause pleiotropic changes in glucose homeostasis, which could exacerbate the pathophysiology of pre-existing diabetes or result in new disease processes.

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