Dual-light defined <i>in situ</i> oral mucosal lesion therapy through a mode switchable anti-bacterial and anti-inflammatory mucoadhesive hydrogel
Huijie LiuThe Affiliated Stomatological Hospital of Nanchang University, The Key Laboratory of Oral Biomedicine, Jiangxi Province Clinical Research Center for Oral Diseases, Nanchang University, Nanchang, Jiangxi, 330006, P.R. ChinaQun LiThe Affiliated Stomatological Hospital of Nanchang University, The Key Laboratory of Oral Biomedicine, Jiangxi Province Clinical Research Center for Oral Diseases, Nanchang University, Nanchang, Jiangxi, 330006, P.R. ChinaYingying XuThe Affiliated Stomatological Hospital of Nanchang University, The Key Laboratory of Oral Biomedicine, Jiangxi Province Clinical Research Center for Oral Diseases, Nanchang University, Nanchang, Jiangxi, 330006, P.R. ChinaYue SunCollege of Chemistry and Chemical Engineering of Nanchang University, Nanchang University, Nanchang, Jiangxi, 330088, P.R. ChinaXinxiang FanThe Affiliated Stomatological Hospital of Nanchang University, The Key Laboratory of Oral Biomedicine, Jiangxi Province Clinical Research Center for Oral Diseases, Nanchang University, Nanchang, Jiangxi, 330006, P.R. ChinaHuaqiang FangThe National Engineering Research Center for Bioengineering Drugs and the Technologies Institute of Translational Medicine, Nanchang University, Nanchang, Jiangxi, 330088, P.R. ChinaBinbin HuThe National Engineering Research Center for Bioengineering Drugs and the Technologies Institute of Translational Medicine, Nanchang University, Nanchang, Jiangxi, 330088, P.R. ChinaLi HuangThe National Engineering Research Center for Bioengineering Drugs and the Technologies Institute of Translational Medicine, Nanchang University, Nanchang, Jiangxi, 330088, P.R. ChinaLan LiaoThe Affiliated Stomatological Hospital of Nanchang University, The Key Laboratory of Oral Biomedicine, Jiangxi Province Clinical Research Center for Oral Diseases, Nanchang University, Nanchang, Jiangxi, 330006, P.R. ChinaXiaolei WangCollege of Chemistry and Chemical Engineering of Nanchang University, Nanchang University, Nanchang, Jiangxi, 330088, P.R. China
2023en
ABI
Annotatsiya
ZPTA-G/HMA can treat oral mucosal lesions by in situ anchoring to wet mucosa surface for hemostasis and the production of ROS for anti-bacteria under GL irradiation, as well as by enhanced anti-inflammation for promoting healing with NIR irradiation.
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