Antioxidant Hispidin Derivatives from Medicinal Mushroom Inonotus hispidus
Li-feng ZanCollege of Plant Sciences, Jilin UniversityJianchun QinCollege of Plant Sciences, Jilin UniversityYa-mei ZhangCollege of Plant Sciences, Jilin UniversityYan-hua YaoCollege of Plant Sciences, Jilin UniversityHai-ying BaoEngineering Research Centre of Edible and Medicinal Fungi, Ministry of Education, Jilin Agricultural UniversityXiang LiCollege of Plant Sciences, Jilin University
2011en
ABI
Annotatsiya
Two natural antioxidants, named inonotusin A (1) and B (2), were isolated from the methanolic extract of the fruit bodies of Inonotus hispidus, together with (E)-4-(3,4-dihydroxyphenyl)but-3-en-2-one (3), hispidin (4) and 3,4-dihydroxybenzaldehyde (5). Their structures were identified by means of extensive NMR and MS data analysis. Compounds 1, 2 and 4 exhibited significant scavenging activity against the 2,20-azinobis(3-ethylbenzhiazoline-6-sulfonate) (ABTS) radical cation. Compound 1 also showed moderate cytotoxicity against a human breast carcinoma cell line (MCF-7) with IC(50) values of 19.6 µM.
Hali tarjima qilinmagan
Identifikatorlar
Iqtiboslar va manbalar
2 ta iqtibos0 ta foydalanilgan manba