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The Critical Need for CD4 Help in Maintaining Effective Cytotoxic T Lymphocyte Responses

Spyros A. KalamsFrom the Partners AIDS Research Center and Infectious Disease Division, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts 02129Bruce D. WalkerFrom the Partners AIDS Research Center and Infectious Disease Division, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts 02129
1998en
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For many viral infections, resolution of illness is associated with long-term host control of viremia rather than viral eradication. An example is EBV infection, and the fact that host immune suppression is associated with EBV-induced disease suggests that it is the immune system that is holding the

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