An efficient one‐pot synthesis of diarylpyrazolo[1,5‐<i>a</i>]pyrimidine from isoflavones
Zun‐Ting ZhangKey Laboratory of the Ministry of Education for Medicinal Resources and Natural Pharmaceutical Chemistry, National Engineering Laboratory for Resource Development of Endangered Crude Drugs in Northwest of China, and School of Chemistry and Materials Science, Shaanxi Normal University, Xi'an 710062, People's Republic of ChinaYu‐Qing MaKey Laboratory of the Ministry of Education for Medicinal Resources and Natural Pharmaceutical Chemistry, National Engineering Laboratory for Resource Development of Endangered Crude Drugs in Northwest of China, and School of Chemistry and Materials Science, Shaanxi Normal University, Xi'an 710062, People's Republic of ChinaYong LiangKey Laboratory of the Ministry of Education for Medicinal Resources and Natural Pharmaceutical Chemistry, National Engineering Laboratory for Resource Development of Endangered Crude Drugs in Northwest of China, and School of Chemistry and Materials Science, Shaanxi Normal University, Xi'an 710062, People's Republic of ChinaDong XueKey Laboratory of the Ministry of Education for Medicinal Resources and Natural Pharmaceutical Chemistry, National Engineering Laboratory for Resource Development of Endangered Crude Drugs in Northwest of China, and School of Chemistry and Materials Science, Shaanxi Normal University, Xi'an 710062, People's Republic of ChinaQing HeKey Laboratory of the Ministry of Education for Medicinal Resources and Natural Pharmaceutical Chemistry, National Engineering Laboratory for Resource Development of Endangered Crude Drugs in Northwest of China, and School of Chemistry and Materials Science, Shaanxi Normal University, Xi'an 710062, People's Republic of China
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Abstract Direct synthetic methods of 6,7‐diphenylpyrazolo[1,5‐ a ]pyrimidine derivatives have been developed. Cyclocondensation of isoflavones with 3‐aminopyrazole in the presence of sodium methoxide as alkali promoter gave 6,7‐diphenylpyrazolo[1,5‐ a ]pyrimidines in moderate to good yields. J. Heterocyclic Chem., (2011).
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