Synthesis of 3,5‐disubstituted 1,3,4‐oxadiazole‐2‐thiones as potential fungicidal agents
B. N. GoswamiDivision of Synthetic Organic Chemistry, Regional Research Laboratory, Jorhat-785006, IndiaJ. C. S. KatakyDivision of Synthetic Organic Chemistry, Regional Research Laboratory, Jorhat-785006, IndiaJ. N. BaruahDivision of Synthetic Organic Chemistry, Regional Research Laboratory, Jorhat-785006, IndiaSomsubhra NathMedicinal and Economic Plant Division, Regional Research Laboratory, Jorhat-785006, India
1984en
ABI
Annotatsiya
Abstract Sixteen new 3‐arylaminomethyl‐5‐(2,4‐dichlorophenyl)‐1,3,4‐oxadiazole‐2‐thione and six 3‐alkyl aryl alkyl‐5‐(2,4‐dichlorophenyl)‐1,3,4‐oxadiazole‐2‐thiones were synthesised and characterised by their sharp melting points, elemental analysis, ir, 1 H nmr and mass spectra. These substituted oxadiazolethiones were screened for their fungitoxic properties. Most of the compounds showed toxicity against two test organisms, Curvularia verruciformis and Alternaria tenuis . The degree of inhibition ranged from 38‐‐100% for a few compounds.
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