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The role of membrane structure in activation of mitochondrial phospholipases. 2. Mechanism of crambin action on the activities of mitochondrial membrane phospholipases and microviscosity.

Tadgibaeva EtDepartment of Biology, Tashkent State University, Vuzgorodok, Republic of UzbekistanVagina OnZamaraeva MvGagel'gans AiTukfatullinaSalakhutdinov BaAripov TF
PubMedrepository1999en
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Effects of crambin on the phospholipase activity, lipid peroxidation and structure of mitochondrial membranes have been investigated. Crambin has been shown to inhibit lipid peroxidation and phospholipase activity induced by Ca2+ and freezing-thawing of mitochondria. As shown by ESR studies, these effects are based on the ability of crambin to cause changes in mitochondrial membrane structure.

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