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Phytochemical and biological investigations of Amaryllidaceae alkaloids: a review

Yan DingInstitute of Chemistry and Applications of Plant Resources, Dalian Polytechnic University, Dalian 116034, ChinaDan QuSchool of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, ChinaKai-Mei ZhangSchool of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, ChinaXiao-Xin CangSchool of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, ChinaZinong KouInstrumental Analysis Center, Dalian Polytechnic University, Dalian 116034, ChinaWei XiaoJiangsu Kanion Pharmaceutical Co. Ltd, Lianyungang 222001, ChinaJingbo ZhuInstitute of Chemistry and Applications of Plant Resources, Dalian Polytechnic University, Dalian 116034, China

2016en

ABI

Annotatsiya

Amaryllidaceae is a family that includes 75 genera and about 1100 species, which have a long history of medicinal use. Many plants have been proven to possess efficacy for neurological injury and inflammatory conditions. This article summarizes 357 Amaryllidaceae alkaloids, and cites 166 174 references over the last three decades. These alkaloids are classified into 14 skeleton types, and their abundant sources are also included. Modern pharmacology studies demonstrate that alkaloids that exclusively occur in Amaryllidaceae plant possess wide-ranging pharmacological actions, especially effects on the central nervous system, as well as antitumor, antimicrobial, and anti-inflammatory activities. Effective monomeric compounds from Amaryllidaceae screened for pharmacological activity in vivo and in vitro are also summarized.

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DOI: 10.1080/10286020.2016.1198332

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