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Thioglycosides in sequential glycosylation strategies

Jeroen D. C. CodéeLeiden Institute of Chemistry, Leiden University, P. O. Box 9502, 2300 RA Leiden, The NetherlandsRemy E. J. N. LitjensLeiden Institute of Chemistry, Leiden University, P. O. Box 9502, 2300 RA Leiden, The NetherlandsLeendert J. van den BosLeiden Institute of Chemistry, Leiden University, P. O. Box 9502, 2300 RA Leiden, The NetherlandsHerman S. OverkleeftLeiden Institute of Chemistry, Leiden University, P. O. Box 9502, 2300 RA Leiden, The NetherlandsGijsbert A. van der MarelLeiden Institute of Chemistry, Leiden University, P. O. Box 9502, 2300 RA Leiden, The Netherlands
2005en
ABI

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This tutorial review surveys the use of thioglycosides in the development of sequential glycosylation methodologies, with a focus on chemoselective, orthogonal and iterative glycosylation strategies reported since the beginning of this century. Both fundamental aspects of glycosidic bond formation and ingenious state-of-the-art methodologies are presented.

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