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Whence Interferon? Variety in the Production of Interferon in Response to Viral Infection

David E. LevyMolecular Oncology and Immunology Program, Department of Pathology and Kaplan Comprehensive Cancer Center, New York University School of Medicine, New York, NY 10016
2002en
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The type I IFNs (IFN-α and IFN-β) were first characterized as cytokines capable of inducing an antiviral state in sensitive target cells ([1][1]). They were originally classified as leukocyte IFN and fibroblast IFN, respectively, to designate their distinct presumptive cellular origins. This

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