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Statistical predictions with glmnet

Solveig EngebretsenDivision for Infection Control and Environmental Health, Department of Infectious Disease Epidemiology and Modelling, Norwegian Institute of Public Health, Oslo, NorwayJon BohlinCentre for Fertility and Health (CEFH), Norwegian Institute of Public Health, Oslo, Norway
2019en
ABI

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Elastic net type regression methods have become very popular for prediction of certain outcomes in epigenome-wide association studies (EWAS). The methods considered accept biased coefficient estimates in return for lower variance thus obtaining improved prediction accuracy. We provide guidelines on how to obtain parsimonious models with low mean squared error and include easy to follow walk-through examples for each step in R.

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