A paper-based dual functional biosensor for safe and user-friendly point-of-care urine analysis
Yujia LiDepartment of Chemistry, University College London, London, WC1E 7JE, UKYingqi KongDepartment of Chemistry, University College London, London, WC1E 7JE, UKYubing HuDepartment of Chemical Engineering, Imperial College London, London, SW7 2AZ, UKYixuan LiDepartment of Chemistry, University College London, London, WC1E 7JE, UKRica AsrosaDepartment of Chemistry, University College London, London, WC1E 7JE, UKWenyu ZhangDepartment of Materials, University of Oxford, Parks Road, Oxford, OX1 3PH, UKBuddha Deka BoruahInstitute for Materials Discovery, University College London, London, WC1E 7JE, UKAli K. YetisenDepartment of Chemical Engineering, Imperial College London, London, SW7 2AZ, UKAndrew DavenportUniversity College LondonTung‐Chun LeeInstitute for Materials Discovery, University College London, London, WC1E 7JE, UKBing LiInstitute for Materials Discovery, University College London, London, WC1E 7JE, UK
2024en
ABI
Annotatsiya
. This dual function biosensor was validated using clinical urine samples, where a correlation coefficient of 0.96 for pH and 0.98 for glucose detection was achieved with commercial methods as references. More importantly, the urine sampling vial was kept sealed throughout the sample-to-result process, which minimised the health risk to frontline practitioners and simplified the diagnostic procedures. This diagnostic platform, therefore, holds high promise as a rapid, accurate, safe, and user-friendly point-of-care (POC) technology for the analysis of urinary biomarkers in frontline clinical settings.
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