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A DFT/TD-DFT investigation of clozapine adsorption on B <sub>12</sub> Y <sub>12</sub> (Y = N, P) nanocages as vehicles for applications in schizophrenia treatment

Charly Tedjeuguim TsapiResearch Unit of Noxious Chemistry and Environmental Engineering, Department of Chemistry, Faculty of Science, University of Dschang, P.O. Box 67, Dschang, CameroonStanley Numbonui TashehDepartment of Chemistry, Faculty of Science, The University of Bamenda, P.O. Box 39 Bambili, Bamenda, CameroonAymard Didier Tamafo FouéguéNumbonui Angela BeriDepartment of Chemistry, Faculty of Science, The University of Bamenda, P.O. Box 39 Bambili, Bamenda, CameroonCaryne Isabelle Lekeufack AlongamoResearch Unit of Noxious Chemistry and Environmental Engineering, Department of Chemistry, Faculty of Science, University of Dschang, P.O. Box 67, Dschang, CameroonEmmanuel Dassi AtongoSchool of Chemical and Biomolecular Sciences, Southern Illinois University Carbondale, IL, 62901, USAJulius Numbonui GhogomuDepartment of Chemistry, Faculty of Science, The University of Bamenda, P.O. Box 39 Bambili, Bamenda, Cameroon
2025en
ABI

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nanocages as promising nanocarriers for targeted clozapine delivery, combining stable binding with the potential for efficient and controlled drug release and, however, warranting experimental validation for addressing current challenges in schizophrenia therapy.

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