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Energy Balance and Obesity

James O. HillFrom the University of Colorado Anschutz Medical Campus, AuroraHolly R. WyattFrom the University of Colorado Anschutz Medical Campus, AuroraJohn C. PetersFrom the University of Colorado Anschutz Medical Campus, Aurora
2012en
ABI

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This article describes the interplay among energy intake,energy expenditure, and body energy stores and illus-trates how an understanding of energy balance can help us develop strategies to reduce obesity. First, reducing obesity requires modifying both energy intake and energy expendi-ture, not simply focusing on either alone. Food restriction alone will not be effective in reducing obesity if human physiology is biased toward achieving energy balance at a high energy flux (ie, at a high level of energy intake and expenditure). In previous environments, a high energy flux was achieved with a high level of physical activity, but in today’s sedentary environment, it is increasingly achieved through weight gain. Matching energy intake to a high level of energy expenditure will likely be more feasible for most people than restricting food intake to meet a low level of energy expenditure. Second, from an energy balance point of

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