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NEUROENDOCRINE DETERMINANTS OF POSTPARTUM PSYCHOEMOTIONAL STATE AND THEIR IMPACT ON LACTATION EFFICIENCY: A COMPREHENSIVE REVIEW

Abdukodirov E.ITashkent State Medical UniversitySirozhiddinova N.STashkent State Medical UniversityInoyatova S.O.Tashkent State Medical UniversityMuradova M.S.Tashkent State Medical UniversityBabakulov Sh.HTashkent State Medical UniversityKaxramonova S.BTashkent State Medical UniversityYusupova Sh.R.Tashkent State Medical University
Open MINDrepository2026
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The postpartum period is characterized by profound physiological and neuroendocrine transformations. This transitional phase involves a critical interplay between the establishment of lactation and the mother's psychoemotional state. In clinical practice, lactational insufficiency and perinatal mood disorders frequently co-occur. This article analyzes the psychoemotional changes occurring during lactation, their underlying neuroendocrine mechanisms, and their correlation with breastfeeding failure. Based on a comprehensive review of scientific literature, it is concluded that shared hormonal and neuroregulatory systems participate in the pathogenesis of both lactation and perinatal depression.

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