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PATHOGENETIC RELATIONSHIP BETWEEN ADENOKINES AND BRONCHO-OBSTRUCTIVE SYNDROME IN CHILDREN WITH OVERWEIGHT

Sidrasulieva Aziza BekbergenovnaTashkent City Multidisciplinary Hospital, Pediatrician
Open MINDrepository2026
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This study investigates the pathogenetic relationship between adenokines and broncho-obstructive syndrome (BOS) in overweight children. The research highlights the role of adipose tissue-derived cytokines in the inflammatory processes contributing to airway obstruction. The study utilized a combination of biochemical analyses, clinical assessments, and statistical modeling to evaluate the correlation between specific adenokines (leptin, adiponectin, resistin) and the severity of BOS. Results indicate that altered adenokine profiles in overweight children are significantly associated with increased risk and severity of broncho-obstructive episodes. These findings provide insights into potential therapeutic targets and underscore the importance of weight management in pediatric respiratory health.

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