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Chemical Constituents of Prangos tschimganica; Structure Elucidation and Absolute Configuration of Coumarin and Furanocoumarin Derivatives with Anti-HIV Activity.

Yasuhiro ShikishimaFaculty of Pharmaceutical Sciences, University of TokushimaYoshihisa TakaishiFaculty of Pharmaceutical Sciences, University of TokushimaGisho HondaFaculty of Pharmaceutical Sciences, University of TokushimaMichiho ItoFaculty of Pharmaceutical Sciences, Kyoto UniversityYoshio TakedaFaculty of Integrated Arts and Sciences, University of TokushimaOlimjon K. KODZHIMATOVFaculty of Pharmaceutical Sciences, University of TokushimaOzodbek AshurmetovAcademy of Sciences, Uzbekistan Institute of BotanyKuo‐Hsing Lee
ABI

Abstract

The methanol extract of the dried aerial parts of Prangos tschimganica gave three new coumarin derivatives and 30 known coumarin derivatives. Their structures were established on the basis of chemical and spectroscopic evidence. Absolute configuration of the isolated compounds were determined by using a modified Mosher's method. Some of the isolated compounds showed anti-HIV activity.

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