GLIOMA: A PATHOLOGIC ANALYSIS OF 150 CASES
Abstract
Objective To observe the cytological heterogenesis of glioma and analyze its effect on the tumor therapy and prognosis.Methods The data of 150 patients with glioma resected in this hospital,from January 2005 to June 2006,were collected and analyzed histologically.Results Sixty-nine gliomas(46%) showed more than two kinds of cellular differentiation.Astrocytoma(5%),anaplastic astrocytoma(77%),oligodendroglial tumor(26%),glioblastoma(60%) and all the seven-mixed gliocytomas had more than two kinds of cellular differentiation and this type of differentiation was also seen in six of eight recurrent astrocytomas.Conclusion Cellular heterogenesis of gliomas shows close relationship with the progression of the tumors.A further study of the tumor differentiation may bring about an active effect on the therapy and prognosis of the disease.