Article

Effects of hydrolysable tannins on native and artificial biological membranes

Marina P. BorisovaInstitute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, ul. Institutskaja, 3, Pushchino, Moscow oblast, 142290, RussiaА. А. КатаевInstitute of Cell Biophysics, Russian Academy of Sciences, ul. Institutskaja, 3, Pushchino, Moscow oblast, 142290, RussiaS. M. MavlyanovInstitute of Bioorganic Chemistry, Academy of Sciences of Uzbekistan, ul. Kh. Abdullaeva, 83, Tashkent, 100125, UzbekistanNodira AbdullajanovaInstitute of Bioorganic Chemistry, Academy of Sciences of Uzbekistan, ul. Kh. Abdullaeva, 83, Tashkent, 100125, Uzbekistan

Biochemistry (Moscow) Supplement Series A Membrane and Cell Biologyjournal2015en

ABI

Abstract

Effects of hydrolysable tannins on plasma membranes of Chara corallina giant cells and lipid bilayer membrane (BLM) were studied. Tannin inhibited chloride channels of alga cell membranes in a dose-dependent manner. Current jumps emerging in BLM in the presence of tannin suggest formation of ion channels, predominantly anion selective. The presence of cholesterol in BLM increased the open state lifetime of the channels. The findings indicate that hydrolysable tannins possess a membrane activity and are capable to form anion channels in a cell membrane.

Topics

Protein Hydrolysis and Bioactive Peptides Biochemical Analysis and Sensing Techniques Analytical Chemistry and Chromatography

Identifiers

DOI: 10.1134/s1990747814040023

Citations and references

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