Synthesis Of 2,5-Dimersapto-1,3,4-Thiadiazol Products
Jololiddinov Fazliddin Yuldashali UgliXaitboev XamidBoboev Baxrom NurillaevichDoctor Of Chemical Sciences, Professor, Head Of The Department Of Chemistry Of Natural Compounds, Faculty Of Chemistry, National University Of Uzbekistan
ABI
Abstract
Potentially bioactive 2,5-bis derivatives of 1,3,4-thiadiazole with alkaloid moieties were synthesized byreaction of 1,3,4-thiadiazol-2,5-dithiol with N-acryloyl-substituted derivatives of the alkaloids anabasine,cytisine, and D-pseudoephedrine.1,3,4-Thiadiazole-2,5-disulfonic acid was synthesized by oxidation of 2,5-dimercapto-1,3,4-thiadiazole,and onium salts of this acid were prepared by its reactions with selected alkaloids and secondaryamines.
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