Article

Study Of The Analgesic Activity Of 1- (4ˊ-Dimethylaminophenyl -) - 6, 7 -Methylenedioxy-1,2,3,4Tetrahydroisoquinoline

Rejepov JumadillaCandidate of Medical Sciences Department of Pharmacology and Toxicology Institute of Chemistry of Plant Substances of the Academy of Sciences of the Republic of UzbekistanKhilola A. RakhmanovaPhD Student Department of Pharmacology and Toxicology Institute of Chemistry of Plant Substances of the Academy of Sciences of the Republic of UzbekistanA. A. AzamatovJunior researcher Department of Pharmacology and Toxicology Institute of Chemistry of Plant Substances of the Academy of Sciences of the Republic of UzbekistanDilfuza SaidkhodjaevaJunior researcher Department of Pharmacology and Toxicology Institute of Chemistry of Plant Substances of the Academy of Sciences of the Republic of Uzbekistan

2020en

ABI

Abstract

The analgesic activity of a new compound 1- (4ˊ-Dimethylaminophenyl -) - 6,7-methylenedioxy-1,2,3,4 tetrahydroisoquinoline was studied under conditions of thermal and chemical irritation on the models “hot plate test”, “acetic writhing”. As a result of the studies carried out, it was found that the researching substance in various doses has an analgesic effect.

Topics

Chemical synthesis and pharmacological studies Synthesis and biological activity Synthesis and Reactions of Organic Compounds

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