Studying the Accumulation of Gadolinium in Human Brain Glioma for Gadolinium-Neutron Capture Therapy
G. A. KulabdullaevInstitute of Nuclear Physics, Academy of Sciences of the Republic of Uzbekistan, 100214, Tashkent, UzbekistanA. A. KimInstitute of Nuclear Physics, Academy of Sciences of the Republic of Uzbekistan, 100214, Tashkent, UzbekistanГ. А. АбдуллаеваInstitute of Nuclear Physics, Academy of Sciences of the Republic of Uzbekistan, 100214, Tashkent, UzbekistanG. T. DjuraevaInstitute of Nuclear Physics, Academy of Sciences of the Republic of Uzbekistan, 100214, Tashkent, UzbekistanI. I. SadikovInstitute of Nuclear Physics, Academy of Sciences of the Republic of Uzbekistan, 100214, Tashkent, UzbekistanB. Kh. YarmatovInstitute of Nuclear Physics, Academy of Sciences of the Republic of Uzbekistan, 100214, Tashkent, UzbekistanM. I. SalimovInstitute of Nuclear Physics, Academy of Sciences of the Republic of Uzbekistan, 100214, Tashkent, UzbekistanRavshanbek T. KadirbekovRepublic Scientific Center of Neurosurgery, 100201, Tashkent, UzbekistanNodirbek R. KadirbekovRepublic Scientific Center of Neurosurgery, 100201, Tashkent, UzbekistanIskandar MavlyanovTashkent Medical Academy, 100109, Tashkent, Uzbekistan
ABI
Abstract
The accumulation of gadolinium in human brain gliomas is estimated after a single intravenous administration of Magnevist. The study is conducted using samples excised during standard surgeries on human brain gliomas. Gadolinium is present in all five examined samples at concentrations of 0.0093 to 0.2384 ng mg–1 (ppm) of tumor tissue.
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