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Hyperoside-loaded TPGs/mPEG-PDLLA self-assembled polymeric micelles: preparation, characterization and <i>in vitro</i>/<i>in vivo</i> evaluation

Xiaoli XiaCollege of Pharmacy, Jiangsu University, Zhenjiang, ChinaJian ZhangCollege of Pharmacy, Jiangsu University, Zhenjiang, ChinaMichael Adu‐FrimpongDepartment of Biochemistry and Forensic Sciences, School of Chemical and Biochemical Sciences, C. K. Tedam University of Technology and Applied Sciences (CKT-UTAS), Navrongo, GhanaXiaoxiao LiCollege of Pharmacy, Jiangsu University, Zhenjiang, ChinaXinyi ShenCollege of Pharmacy, Jiangsu University, Zhenjiang, ChinaQing HeCollege of Pharmacy, Jiangsu University, Zhenjiang, ChinaWanjing RongCollege of Pharmacy, Jiangsu University, Zhenjiang, ChinaHao JiElmurat ToreniyazovTashkent State Agricultural University (Nukus Branch), Nukus, UzbekistanXiming XuCollege of Pharmacy, Jiangsu University, Zhenjiang, ChinaJiangnan YuCollege of Pharmacy, Jiangsu University, Zhenjiang, ChinaQilong WangCollege of Pharmacy, Jiangsu University, Zhenjiang, China
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Abstract

anti-oxidative effect showed obvious strong scavenging DPPH capability of Hyp-PMs, which may be attributed to its smaller size and better solubility. Altogether, Hyp-PMs may serve as a possible strategy to potentially enhance aqueous solubility, bioavailability and anti-oxidative effect of Hyp, which may play a key role in Hyp application in the pharmaceutical industries.

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