Preprint

The Influence of the Nature of the Dispersing Agent on the Interaction of DNA Nucleotides with the Surface of YSZ Nanoparticles and the Homogeneity of Lyophilites Based on Them

Aleksander S. Doroshkevich. Graduate University of Science and Technology Vietnam Academy of Science and Technology Hoang Quoc Viet, Cau Giay, Ha Noi, Viet Nam,V. S. Doroshkevich. Donetsk National University, Ukraine,T. Yu. ZelenyakDonetsk Institute for Physics and Engineering named after O.O. Galkin, Kiev, Ukraine,Nelya V. Doroshkevich. Donetsk National Vasyl Stus University, Vinnitsa, Ukraine,Andriy I. Lyubchyk. Nanotechcenter LLC, Krzhizhanovsky str., 3, Kyiv 03680, Ukraine,Sergiy Lyubchyk. REQUIMTE, Faculdade de Cincias e Tecnologia, Universidade Nova de Lisboa, Quina de Torre, 2829-516 Caparica, Portugal,Andriy Lyubchyk. REQUIMTE, Faculdade de Cincias e Tecnologia, Universidade Nova de Lisboa, Quina de Torre, 2829-516 Caparica, Portugal,Alisa A. Tatarinova. REQUIMTE, Faculdade de Cincias e Tecnologia, Universidade Nova de Lisboa, Quina de Torre, 2829-516 Caparica, Portugal,Anca Stănculescu. Optical Processes in Nanostructured Materials Laboratory, National Institute of Materials Physics, 405A Atomistilor Street, P.O. Box MG-7, 077125 Magurele, Romania,Dan Chicea. Research Center for Complex Physical Systems, Faculty of Sciences, "Lucian Blaga" University of Sibiu, Dr. Ion Ratiu str. no. 5-7, 550012 Sibiu, Romania,Carmen Mîţă. Faculty of Chemistry, "Alexandru Ioan Cuza" University of Iasi, Bld. Carol I, No. 11, 700506 Iasi, Roma-nia,Nicoleta Cornei. Faculty of Chemistry, "Alexandru Ioan Cuza" University of Iasi, Bld. Carol I, No. 11, 700506 Iasi, Roma-nia,Diana MardareDonetsk Institute for Physics and Engineering named after O.O. Galkin, Kiev, Ukraine,Б. Л. Оксенгендлер. Ion-plasma and laser technologies Institute after U. Arifov, Uzbekistan, Tashkent,N. N. Nikiforova. Ion-plasma and laser technologies Institute after U. Arifov, Uzbekistan, Tashkent,M.N. Mirzayev. Institute of Radiation Problems, Azerbaijan National Academy of Sciences, Baku, Z1143 Azerbaijan,E. Popov. Institute for Nuclear Research and Nuclear Energy, Bulgarian Academy of Sciences, Sofia 1784, Bulgaria,A. A. Donkov. Institute of Solid-State Physics, Bulgarian Academy of Sciences, Sofia, 1784, Bulgaria,Vesna Teofilović. University of Novi Sad, Faculty of Technology Novi Sad, Bul. Cara Lazara 1, 21000, Novi Sad, Serbia,B. Jasińska. Institute of Physics, Maria Curie-Skodowska University, Lublin, Poland,L. H. Khiem

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Abstract

A variational analysis of dispersion medium (electrolytes and surfactants) was carried out for the best nucleotide interactions with the presence of nanoparticles and the ability to formation of homogeneous coatings upon drying / lyophilization. Using UV-spectroscopy and transmission electron microscopy, the processes of immobilization of nucleotides on the surface of nanoparti-cles of the composition ZrO2-3mol% Y2O3 (YSZ) in the presence of various dispersing agents were investigated. Promising dispersing agents were established, the optimal composition of suspen-sions based on DNA nucleotides and YSZ nanoparticles, which is potentially suitable for adaptive technologies of bionanoelectronics, was selected. The aim of the work is to obtain and study functional media for molecular electronics based on heterojunctions biological molecule &ndash; wide-gap dielectric.

Topics

DNA and Nucleic Acid Chemistry thermodynamics and calorimetric analyses Advanced biosensing and bioanalysis techniques

Identifiers

DOI: 10.20944/preprints202304.0346.v1

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