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Work: Scaffold-Hopping Design and Synthesis of Thieno[3,2-d]pyrimidines: Anticancer Activity, Apoptosis Induction, and In Silico Inhibition of CDKs

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Works cited by this work

Synthesis, characterization, and antimicrobial activity of novel hydrazone-bearing tricyclic quinazolines

Thieno[2,3-d]pyrimidin-4-ones 1. Condensation of 2,3-dimethyl- and 2,3-tri-, 2,3-tetra-, and 2,3-pentamethylene-7,8-dihydro-pyrrolo[1,2-a]thieno[2,3-d]pyriminidin-4(6H)-ones with aromatic aldehydes and furfural

Design, synthesis, in vitro evaluation of a new pyrrolo[1,2‐<i>a</i>]thiazolo[5,4‐<i>d</i>]pyrimidinone derivatives as cholinesterase inhibitors against Alzheimer's disease

Parallel synthesis of condensed pyrimidine-thiones and their antitumor activities

A Convenient One-pot Synthesis of 2,3-Disubstituted Thieno[2,3-d]pyrimidin-4(3H)-ones from 2H-Thieno[2,3-d][1,3]oxazine-2,4(1H)-diones, Aromatic Aldehydes and Amines

Synthesis of tricyclic pyrazolopyrimidine arylidene ester derivatives and their cytotoxic and molecular docking evaluations

Synthesis and Biological Activities of Dihydrooxazolo[5,4-<i>d</i>]-pyrrolo[1,2-<i>a</i>]pyrimidinones

Furo[2,3‐<i>d</i>]pyrimidines as Mackinazolinone/Isaindigotone Analogs: Synthesis, Modification, Antitumor Activity, and Molecular Docking Study

Synthesis and Antitumor Activity of Novel Linear Tricyclic Compounds Derived from Purine

Novel nor-harmal alkaloid from Adhatoda vasica

Discovery of novel (E)-1-methyl-9-(3-methylbenzylidene)-6,7,8,9-tetrahydropyrazolo[3,4-d]pyrido[1,2-a]pyrimidin-4(1H)-one as DDR2 kinase inhibitor: Synthesis, molecular docking, and anticancer properties

Novel deoxyvasicinone derivatives as potent multitarget-directed ligands for the treatment of Alzheimer's disease: Design, synthesis, and biological evaluation

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Quinazolines. 3*. synthesis of 6-bromo-8-chloro-sulfonylquinazoline-2,4(1h,3h)-dione and its interaction with nucleophilic reagents

Glide: A New Approach for Rapid, Accurate Docking and Scoring. 1. Method and Assessment of Docking Accuracy

Imidazole Hybrids: A Privileged Class of Heterocycles in Medicinal Chemistry with New Insights into Anticancer Activity

Multi-stage mechanisms of tumor metastasis and therapeutic strategies

Design, synthesis, biological evaluation of a new tricyclicthiazolopy‐rimidinone derivatives as acetylcholinesterase inhibitors

Chromatin condensation during apoptosis requires ATP

Design and synthesis of some new thiophene, thienopyrimidine and thienothiadiazine derivatives of antipyrine as potential antimicrobial agents

Metastasis: a question of life or death

Classification of scaffold-hopping approaches

Recent Advances in Scaffold Hopping

Design, Synthesis, and Biological Evaluation of 6-Substituted Thieno[3,2-<i>d</i>]pyrimidine Analogues as Dual Epidermal Growth Factor Receptor Kinase and Microtubule Inhibitors

Tumor cell migration in complex microenvironments