Article

SYNTHESIS OF (E)-5-(3,4-DIMETHOXYBENZYLIDENE)-3-METHYL-6,7-DIHYDROPYRROLO[1,2-a]THIENO[3,2d]PYRIMIDIN-9(5H)-ONE

Anvarjon BURONOV Azizbek NASRULLAEVPhD student at Sharof Rashidov Samarkand State University, DSc student at Sharof Rashidov Samarkand State UniversityNie LIFEI Khurshed BOZOROVProfessor at The Xinjiang Technical Institute of Physics & Chemistry. CAS, Professor at Samarkand State University named after Sharof Rashidov Professor at The Xinjiang Technical Institute of Physics & Chemistry. CASHaji Akber AisaProfessor at The Xinjiang Technical Institute of Physics & Chemistry. CAS

ŬzMU habarlari.journal2025en

ABI

Abstract

(E)-5-(3,4-Dimethoxybenzylidene)-3-methyl-6,7-dihydropyrrolo[1,2-a]thieno[3,2-d]pyrimidin-9(5H)-one (AR-109) was synthesized in two steps from ethyl 3-amino-5-bromobenzo[b]thiophene-2-carboxylate (AT-2). 1H and 13C NMR, HRMS confirmed the structure. Increased reaction temperature and duration significantly improved yield. These derivatives hold promise for pharmaceutical and material applications.

Topics

Synthesis of Organic Compounds Synthesis and biological activity Synthesis of heterocyclic compounds

Identifiers

DOI: 10.69617/nuuz.v3i3.1.7512

Citations and references

Cited by 08 references

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