Article

ALAI MUMIYO (SHILAJIT): TRADITIONAL ORIGINS AND EXPERIMENTAL EVIDENCE OF ANTICOAGULANT AND FIBRINOLYTIC ACTIVITY

Zagrutdinov, FanilAndijan State Medical Institute, Department of Pharmacology, Clinical Pharmacology, and Medical Biotechnology

Zenodo (CERN European Organization for Nuclear Research)repository2025

ABI

Abstract

The effect of Alai mumiyo extract (25 mg/kg) on blood coagulation in dogs was studied. Ten healthy animals received the extract orally, and coagulation parameters were measured at baseline, 30, and 60 minutes. The extract significantly prolonged clotting, recalcification, and thrombin times, increased plasma tolerance to heparin, and enhanced fibrinolytic activity (p < 0.05). Fibrinogen levels slightly decreased, while coagulation factor activities and total protein remained unchanged. Alai mumiyo exhibits anticoagulant and fibrinolytic effects, indicating potential for natural modulation of hemostasis.

Topics

Hemostasis and retained surgical items Animal health and immunology Polysaccharides and Plant Cell Walls

Identifiers

DOI: 10.5281/zenodo.17535342

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