Cytotoxic Activity of 1,2,4-Triazole Derivatives as Nucleoside Analogues with Antiviral Potential
Nigora ToshevaAcad. S.Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, MirzoUlugbek Str. 77, Tashkent, 100170, Uzbekistan; [email protected]Sobirdjan SasmakovAcad. S.Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, MirzoUlugbek Str. 77, Tashkent, 100170, Uzbekistan; [email protected]Shakhnoz Sadikovna AzimovaAcad. S.Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, MirzoUlugbek Str. 77, Tashkent, 100170, Uzbekistan; [email protected]
Open MINDrepository2026
ABI
Abstract
The cytotoxic activity of 1,2,4-triazole–containing nucleoside analogues was evaluated in tumor and normal cell lines. The compounds showed no cytotoxic effects, in contrast to reference drugs, indicating high selectivity and supporting their potential as safe antiviral agents.
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