One-Pot Synthesis of Simple Alkaloids: 2,3-Polymethylene-4(3<i>H</i>)-quinazolinones, Luotonin A, Tryptanthrin, and Rutaecarpine
Katherine Chae JahngCollege of Pharmacy, Yeungnam UniversitySeung Ill KimCollege of Pharmacy, Yeungnam UniversityDong Hyeon KimCollege of Pharmacy, Yeungnam UniversityChang‐Seob SeoCollege of Pharmacy, Yeungnam UniversityJong‐Keun SonCollege of Pharmacy, Yeungnam UniversitySeung Ho LeeCollege of Pharmacy, Yeungnam UniversityEung Seok LeeCollege of Pharmacy, Yeungnam UniversityYurngdong JahngCollege of Pharmacy, Yeungnam University
2008en
ABI
Abstract
One-pot synthesis of various 2,3-polymethylene-4(3H)-quinazolinones from anthranilic acid, corresponding lactam and SOCl(2) is described, which can be applicable to the synthesis of simple 4(3H)-quinazolinone-derived alkaloids, such as luotonin A, tryptanthrin, and rutaecarpine.
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