Обзорная статья

The effect of flaxseed oil consumtion on blood pressure among patients with metabolic syndrome and related disorders: A systematic review and meta‐analysis of randomized clinical trials

Trias MahmudionoDepartment of Nutrition, Faculty of Public Health Universitas Airlangga Surabaya IndonesiaSaade Abdalkareem JasimAl‐maarif University College Medical Laboratory Techniques Department Al‐anbar‐Ramadi IraqYasir Salam KarimDepartment of Pharmacy Al‐Manara College for Medical Sciences Maysan IraqDmitry Olegovich BokovInstitute of Pharmacy Sechenov First Moscow State Medical University Moscow Russian FederationWalid Kamal AbdelbassetDepartment of Health and Rehabilitation Sciences College of Applied Medical Sciences, Prince Sattam bin Abdulaziz University Al Kharj Saudi ArabiaKholmurod S. AkhmedovProfessor, Doctor of Medical Sciences, Head of the Department of Internal Diseases No.3 Tashkent Medical Academy Tashkent UzbekistanGhulam YasinDepartment of Botany Bahauddin Zakariya University Multan PakistanLakshmi ThangaveluCenter for Transdisciplinary Research, Department of Pharmacology, Saveetha Dental College, Saveetha Institute of Medical and Technical Science Saveetha University Chennai IndiaYasser Fakri MustafaDepartment of Pharmaceutical Chemistry, College of Pharmacy University of Mosul Mosul IraqShehla ShoukatPlant Genomics and Biotechnology, National Institute for Genomics and Advanced Biotechnology National Agricultural research centre Islamabad PakistanMazin A. A. NajmPharmaceutical Chemistry Department College of Pharmacy, Al‐Ayen University Thi‐Qar IraqMohammad AmraeiKuhdasht Health Center Lorestan University of Medical Sciences Khorramabad Iran

Phytotherapy Researchjournal2022en

ABI

Аннотация

We systematically reviewed randomized clinical trials (RCTs) to elucidate the overall effects of flaxseed oil consumption on blood pressure (BP) in patients with metabolic syndrome and related disorders. PubMed, Scopus, Cochrane Library, and ISI Web of Science databases were systematically searched until March 31, 2020, to find RCTs that examined the effect of flaxseed oil consumption on BP. Weighed mean difference (WMD) was pooled using a random-effects model. Standard methods were used for the assessment of heterogeneity, sensitivity analysis, and publication bias. Meta-analysis of five trials (6 arms) showed significant reductions in systolic (WMD: -3.86 mmHg, 95% CI: -7.59 to -0.13, p = .04) BP (SBP) after flaxseed oil consumption. However, the overall effect illustrated no significant change in diastolic (WMD: -1.71 mmHg, 95% CI: -3.67 to 0.26, p = .09) BP (DBP) in the intervention group compared with the control group. Our findings revealed that flaxseed oil consumption has favorable effects on SBP in patients with metabolic syndrome and related disorders. However, further investigations are needed to provide more reliable evidence.

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Темы

Nutritional Studies and Diet Diet, Metabolism, and Disease Diet and metabolism studies

Идентификаторы

DOI: 10.1002/ptr.7566

Цитирования и источники

Цитирований: 0Использованных источников: 61

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