ASSESSMENT OF THE QUALITY OF LIFE AND PSYCHO-EMOTIONAL STATE OF PATIENTS WITH SHERESHEVSKY-TURNER SYNDROME
Аннотация
<strong>The purpose of the study. To </strong>study the indicators of quality of life in patients with Shereshevsky-Turner syndrome. <strong>Material and methods. </strong>The study included 69 females aged 16 to 23 years, the average age was 20.3±1.9 years. The main group included 43 patients with STS, mean age was 20.1±1.3 years. The control group included 26 healthy individuals aged 20.5±2.6 years. The groups were comparable in terms of age (p=0.40) and BMI (p=0.29). To assess the quality of life of patients, a short version of the MOS 36-Item Short-Form Health Survey (MOS SF-36) was used. The 36 items on the questionnaire are grouped into eight scales: physical functioning (PF), role functioning (RP), bodily pain (BP), general health (GH), vital activity (VT), social functioning (SF), role emotional functioning (RE) and mental health (MH). <strong>Results and discussion. </strong>The analysis of the parameters of the physical component of health showed that the integral indicator of the physical component of health (PCH) varied from 53.3 to 58.4 points with Me 55.8 points in STS. These indicators are significantly lower than the control values (Me 76.6; IQR 71.4-80.5). Adolescent girls with STS are at high risk of developing problems associated with lower social activity, poor social coping skills, and increased immaturity, hyperactivity, and impulsivity compared to their peers. In addition, patients with STS often have difficulty maintaining relationships with their peers. <strong>Conclusions. </strong>The main clinical signs of STS in the studied cohort were short stature, primary amenorrhea, sexual infantilism, a significant proportion of patients have a wide chest, X-shaped curvature of the legs, skin folds on the neck, more than a third were diagnosed with arterial hypertension. According to the results of the survey, there is a significant decrease in the parameters of the physical (by 26.5%) and psychological (29.3%) components of health and quality of life.