Sensory Characteristics and Impact of Flavanol-Rich Grape and Blueberry Extract on Blood Flow Velocity and Oxidative Stress

BACKGROUND: Several epidemiological studies and intervention trials have demonstrated that grapes and blueberries, which are rich in flavanols, can lower the risk of cardiovascular disease. However, the mechanisms of action of these compounds remain unclear due to their low bioavailability. OBJECTIVE: This study aimed to characterize the sensory properties, blood flow velocity, and oxidative stress of a polyphenol rich grape and blueberry extract (PEGB) containing approximately 16% flavanols (11% monomers and 4% dimers). METHOD: was also compared with quercetin utilizing a luminescence method. Furthermore, the effect of a single administration of PEGB on the blood flow velocity of skeletal muscle arterioles was investigated using a laser Doppler method in rats. RESULTS: at high concentrations. In contrast, quercetin demonstrated antioxidant activity. A single oral administration of PEGB significantly increased the blood flow velocity of skeletal muscle arterioles. CONCLUSION: production at low concentrations in neutral pH environments, and significantly enhanced blood flow to skeletal muscle following a single administration to rats. These findings highlight the necessity for further investigation into the causal relationships between oral perception, redox properties, and bioactivity of polyphenols.

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