The Physical Development and Clinical Course of Celiac Disease in Children Depending on Adherence to Diet Therapy

Aim of the study. To assess the clinical features of the typical form of celiac disease and the physical development of children depending on adherence to a gluten-free diet. Materials and methods. The article presents the results of a study involving 50 children aged 1 to 14 years with a newly diagnosed celiac disease. The study was conducted at the Gastroenterology Department of the Republican Specialized Scientific-Practical Medical Center of Pediatrics from 2021 to 2022. Depending on adherence to a gluten-free diet (GFD), all patients were divided into two groups—those who followed diet therapy and those who did not. Results. The findings indicate a wide range of clinical manifestations of celiac disease. Along with enteral syndrome, children with celiac disease showed impaired physical development. The study demonstrated that adherence to a gluten-free diet for 6 months leads to a significantly faster, although not always complete, resolution of gastrointestinal symptoms, a decrease in the severity of extraintestinal manifestations, and a positive effect on anthropometric indicators.

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