Статья

Antimicrobial and Antioxidant Properties of Rosemary and Sage (Rosmarinus officinalis L. and Salvia officinalis L., Lamiaceae) Essential Oils

Biljana BožinFaculty of Medicine, Department of Pharmacy, University of Novi Sad, Hajduk Veljkova 3, 21000 Novi Sad, Serbia, Faculty of Sciences, Deprtment of Chemistry, University of Novi Sad, Trg D. Obradovica 3, Novi Sad, Serbia, and Faculty of Medicine, Department of Pharmacology and Toxicology, University of Novi Sad, Hajduk Veljkova 3, Novi Sad, SerbiaNeda Mimica–DukićFaculty of Medicine, Department of Pharmacy, University of Novi Sad, Hajduk Veljkova 3, 21000 Novi Sad, Serbia, Faculty of Sciences, Deprtment of Chemistry, University of Novi Sad, Trg D. Obradovica 3, Novi Sad, Serbia, and Faculty of Medicine, Department of Pharmacology and Toxicology, University of Novi Sad, Hajduk Veljkova 3, Novi Sad, SerbiaIsidora SamojlikFaculty of Medicine, Department of Pharmacy, University of Novi Sad, Hajduk Veljkova 3, 21000 Novi Sad, Serbia, Faculty of Sciences, Deprtment of Chemistry, University of Novi Sad, Trg D. Obradovica 3, Novi Sad, Serbia, and Faculty of Medicine, Department of Pharmacology and Toxicology, University of Novi Sad, Hajduk Veljkova 3, Novi Sad, SerbiaE JovinFaculty of Medicine, Department of Pharmacy, University of Novi Sad, Hajduk Veljkova 3, 21000 Novi Sad, Serbia, Faculty of Sciences, Deprtment of Chemistry, University of Novi Sad, Trg D. Obradovica 3, Novi Sad, Serbia, and Faculty of Medicine, Department of Pharmacology and Toxicology, University of Novi Sad, Hajduk Veljkova 3, Novi Sad, Serbia

2007en

ABI

Аннотация

The essential oils of rosemary ( Rosmarinus officinalis L.) and sage ( Salvia officinalis L.) were analyzed by means of gas chromatography-mass spectrometry and assayed for their antimicrobial and antioxidant activities. Antimicrobial activity was tested against 13 bacterial strains and 6 fungi, including Candida albicans and 5 dermatomycetes. The most important antibacterial activity of both essential oils was expressed on Escherichia coli, Salmonella typhi, S. enteritidis, and Shigella sonei. A significant rate of antifungal activity, especially of essential oil of rosemary, was also exhibited. Antioxidant activity was evaluated as a free radical scavenging capacity (RSC), together with the effect on lipid peroxidation (LP). RSC was assessed by measuring the scavenging activity of essential oils on 2,2-diphenyl-1-picrylhydrazil (DPPH) and hydroxyl radicals. Effects on LP were evaluated following the activities of essential oils in Fe(2+)/ascorbate and Fe(2+)/H2O2 systems of induction. Investigated essential oils reduced the DPPH radical formation (IC50 = 3.82 microg/mL for rosemary and 1.78 microg/mL for sage) in a dose-dependent manner. Strong inhibition of LP in both systems of induction was especially observed for the essential oil of rosemary.

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Идентификаторы

DOI: 10.1021/jf0715323

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